Fluoroquinolones Snapshot

Fluoroquinolone SnapShot-General Info About This Class

EXAMPLES:
Levofloxacin (newer)
Ciprofloxacin (older)
Moxifloxacin (newer)
Ofloxacin (older)

INDICATIONS:
Certain suspected or confirmed bacterial pneumonia & other respiratory infections
Certain suspected or confirmed bacterial GI infections
Certain suspected or confirmed bacterial eye infections (in ophthalmic form)
Bacterial sinus infections
Urinary tract infections & pyelonephritis
There are many other uses for this class as it treats a variety of bacterial infections

SPECIFIC BACTERIAL COVERAGE
Haemophilus influenza
Pseudomonas aeruginosa (copra specifically)
Methicillin-sensitive staphylococci
Chlamydia

For a more in depth list – check out Merck manual

POTENTIAL SERIOUS ADVERSE REACTION: (2)
Tendon rupture (black box warning)
Possible permanent peripheral neuropathy
Seizures potential (lowers threshold)
C-diff
QT prolongation
Nephrotoxicity
Hepatotoxicity
Myasthenia graves exacerbation

COMMON SIDE EFFECTS:
Nausea
Insomnia
Headache

CONTRA/CAUTION:
Myasthenia gravis
Renal dysfunction (dosing adjustments will need to be made)
CNS dysfunction disorders

NOTES:
” NSAIDs may enhance the CNS stimulatory effects of fluoroquinolone.” Increases the risk for seizures. “>(1)

REFERENCES:
1. http://www.merckmanuals.com/professional/infectious-diseases/bacteria-and-antibacterial-drugs/fluoroquinolones
2. https://online.epocrates.com/drugs/861/Levaquin

 

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Suffix for Medication Classes (endings)

Note that there are exceptions and variations to the below endings. This is simply a generalization for most or many medications in that specific class.

  1. -Azempam: Benzodiazepine (Anti-anxiety) Example Lorazepam. Note some benzos end differently
  2. -Azole: Anti-fungal (Fungal infections) Example Clotrimazole
    3. -Cillin: Penicillins (Antibiotic) Example Amoxicillin
    4. -Cycline: Tetracycline (Antibiotic) Example Doxycycline
    5. -Dipine: Calcium Channel Blocker (Hypertension) Example Amlodipine
    6. -Floxacin: Fluoroquinolone (Antibitoic) Example Ciprofloxacin
    7.-Lol: Beta Blocker (hypertension) Example Metoprolol
    8. -Mycin: Macrolides (Antibiotic) Example Azithromycin. Note there are also exceptions to this for example Clindamycin is not in this group (it is a Lincosamide)
    9. -Prazole: PPI (Acid reducer) Example Omeprazole
    10. -Pril: Ace Inhibitor (Hypertension) Example Lisinopril
    11. -Sartan: ARB (Hypertension) Example Losartan
    12. -Statin: HMG-CoA reductase inhibitors (Hyperlipidemia) Example Simvastatin
  3. -Tidine: H2 (Acid reducer): Example Ranitidine (Zantac)
    14. -Thiazide: Thiazide diuretic (Hypertension) Example HCTZ-Hydrochlorathiazide

This list are some common ones. There are others. We may update this list gradually

 

ACE Inhibitors Snapshot

EXAMPLES:
Benzapril (Lotensin)
Captopril (Capoten)
Enalapril (Vaster)
Lisinopril (Zestril, Prinvil)
Quinapril (Accupril)
Ramipril (Atlace)

COMBO MEDS
Often combined with HCTZ (diuretic)

INDICATIONS
Hypertension
CHF
MI, acute
Diabetic patient-may actually improve renal function (1)

POTENTIAL SIDE EFFECTS
Angioedema
Dry cough
Hyperkalemia
Hypotension

CONTRAINDICATED
Pregnant
Renal artery stenosis
Renal failure

REFERENCES:
1) http://www.ncbi.nlm.nih.gov/pubmed/11708761
2) Epocrates: https://online.epocrates.com

DISCLAIMER: This is not an all-inclusive list. There are other contraindications, side effects, etc

Beta Blockers Snapshot

Beta Blockers also known as beta-adrenergic blocking agents

EXAMPLES

Atenolol (Tenormin)

Labetalol (Trandate)

Metoprolol (Lopressor, Toprol-XL)

Nadolol (Corgard)

Propanolol (Inderal)

COMBINATIONS

Metoprolol-HCTZ (diuretic)

INDICATIONS

Angina

Atrial fibrillation

Arrythmias

Heart failure

Hypertension

Migrane prophylaxis

Myocardial infarction, acute & post

POTENTIAL SIDE EFFECTS

Bradycardia

Masking sx of hypoglycemia

Hypotension

Bronchodspasms

CONTRA/CAUTION

AV heart blocks 2nd/3rd

Sick sinus syndrome

Pheochromocytoma

Severe PVD, Raynauds

COPD/Asthma (caution)

Myasthenia gravis (caution)

2nd-3rd trimester pregnancy (caution)

NOTES:

Abrupt cessation should be avoided as may cause angina exacerbation, arrhythmia, myocardial infarction, etc. If needing to DC, should be tapered

REFERENCES:

1) Epocrates Drugs

2) http://cvpharmacology.com/cardioinhibitory/beta-blockers

3) Drugs.com

DISCLAIMER: This is a very general overview of this medication class. It is not all-inclusive. Note that there are other uses for different kinds of BB that work well for other conditions such as tremors, migranes, & glaucoma.